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Hemoglobin Variants and beta-Thalassemia Screening

Defects in genes, which are responsible for the synthesis of the hemoglobin molecule, result in a group of hereditary diseases termed as ”hemoglobinopathies”. Depending on the molecular defect, hemoglobinopathies may be classified in ”structural hemoglobin variants” and in ”thalassemias”.

This test kit allows for a reliable separation and identification of the common and clinically significant hemoglobin variants. For beta-thalassemia screening the kit ensures an exact quantification of HbF and HbA2. A ready-to-use test solution (containing HbA1c, HbF, HbA0, HbE, HbA2, HbD, HbS, HbC), a hemolysate calibrator (containing HbF, HbA2) as well as three hemolysate controls are available for quality assurance.

Sample Preparation


Sample Preparation Hemoglobin Variants Whole Blood

Chromatography


Chromatogram Hemoglobin Variants Whole Blood

Ordering Information


Order No.


Description


Quantity


13100


ClinRep® Complete Kit for Hemoglobin Variants and ß-Thalassemia Screening


1 pce.


in Whole Blood for 500 assays


Components of the Complete Kit (order no. 13100):


13101


ClinRep® Reagent Kit


1 pce.


13113


Hemolysate Calibrator HbF/A2, ready for use


5 x 3 ml


13130


Analytical Column with test chromatogram


1 pce.


Manual


1 pce.


Quick Reference


1 pce.


Components of the Reagent Kit (order no. 13101):


13107


Buffer 1


2500 ml


13108


Buffer 2


2500 ml


13109


Washing Solution W


2000 ml


13121


Hemolysis Reagent H


500 ml


Optional Components:


13114


Test Solution (HbA1c/F/A/E/A2/D/S/C), ready for use


5 x 3 ml


Accessories:


11024


Sample vials 1.5 ml without cap


1000 pcs.


FK5810


PEEK tubing (connection of prefilter and column)


1 pce.


FK5820


Stainless steel prefilter holder


1 pce.


FK5821


Replacement filter for stainless steel prefilter holder


10 pcs.


ClinChek® Controls:


13182


Hemolysate Control HbF/A2, Level I, II, ready for use


2 x 5 x 3 ml


13183


Hemolysate Control HbF/A2/S, Level I, ready for use


5 x 3 ml



Download product brochures, product documents (e.g. safety data sheets), and instructions for use.

Please get in touch to order this product.