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Antidepressants

In addition to the classical TCAs a variety of next generation antidepressants (ADP) is available for the treatment of depressions, such as selective serotonin and norepinephrine reuptake inhibitors (SSRIs, SNRIs, NRIs) and TCAs.

The ClinMass® Add-on Set for Antidepressants (order no. MS9400) contains all analyte specific components required for the quantification of 36 different ADPs and metabolites. The ClinMass® TDM Platform (order no. MS9000) contains the components needed for sample preparation and LC-MS/MS analysis. It can be used with all ClinMass® Add-on Sets of the TDM Kit System (BZP, TCA, …). The analytical column is suitable for the whole analyte panel (156 compounds).

Sample Preparation


Sample Preparation Antidepressants Serum Plasma

Chromatography


Chromatogram Antidepressants Serum Plasma

Ordering Information


Order No.


Description


Quantity


MS9000


ClinMass® TDM Platform for 400 assays


1 pce.


Kit Components (order no. MS9000):


MS9005


Autosampler Washing Solution


1000 ml


MS9007


Mobile Phase A


2 x MS9007 (2 x 1000 ml)


MS9008


Mobile Phase B


1000 ml


MS9020


Sample Preparation Vials


4 x MS9020 (4 x 100 pcs.)


MS9021


Precipitant P


2 x MS9021 (2 x 25 ml)


Start Accessories:


MS9030


Analytical Column with test chromatogram


1 pce.


MS9032


Prefilter


1 pce.


Accessories:


MS9022


Diluting Solution D


50 ml


MS9400


ClinMass® Add-on Set for Antidepressants in Serum / Plasma for 200 assays


1 pce.


Kit Components (order no. MS9400):


MS9412


Internal Standard IS, lyophil.


5 x 5 ml


MS9413


Serum Calibrator Set, lyophil. (Level 0 – 3)


4 x 1 x 1 ml


Manual


1 pce.


Start Accessories:


MS9414


Optimisation Mix, lyophil.


2 x 2 ml


ClinChek® Controls:


MS9482


Serum Control, lyophil., Level I, II


2 x 5 x 1 ml



The ClinMass® Add-on Set for Antidepressants (order no. MS9450) contains all analyte specific components required for the quantification of 37 different ADPs and metabolites. The ClinMass® TDM Platform (order no. MS9050) contains the components needed for on-line SPE LCMS/MS analysis. It can be used with all ClinMass® Add-on Sets of the “TDM Kit System, on-line”. The analytical column is suitable for the whole analyte panel (153 compounds).

on-line SPE

Direct injection of sample and Internal Standard IS
in the ratio 1:2 (autosampler).
Direct injection

Chromatography


Chromatogram Antidepressants online SPE Serum Plasma

Ordering Information


Order No.DescriptionQuantity
MS9050ClinMass® TDM Platform, on-line1 pce.
for 400 assays
 
Content
Autosampler Washing Solution1 x MS9005
Mobile Phase A2 x MS9007
Mobile Phase B1 x MS9008
SPE-Buffer Load L2 x MS9059
SPE-Buffer Wash W2 x MS9060
Reconstitution Solution R1 x MS9071
 
Separately available components:
MS9005Autosampler Washing Solution1000 ml
MS9007Mobile Phase A1000 ml
MS9008Mobile Phase B1000 ml
MS9059SPE-Puffer Load L2500 ml
MS9060SPE-Puffer Wash W2500 ml
MS9071Reconstitution Solution R5 ml
 
Start Accessories:
MS9035Analytical Column with test chromatogram1 pce.
MS9031SPE-Column1 pce.
MS9032Prefilter1 pce.
 
Accessories:
MS9022Diluting Solution D50 ml
FK7400Inline-Filter (stainless steel sieve, free of dead volume)1 pce.
FK7340Sealings and sieves for order no. FK74004 pcs. each
 
MS9450ClinMass® Add-on Set, on-line,1 pce.
for Antidepressants in Serum / Plasma
for 400 assays
 
Content:
Internal Standard IS, lyophil.1 x MS9462
Serum Calibrator Set, lyophil. (Level 0 – 3)1 x MS9413
Manual
 
Separately available components:
MS9462Internal Standard IS, lyophil.5 ml
MS9413Serum Calibrator Set, lyophil. (Level 0 – 3)4 x 1 x 1 ml
 
Start Accessory:
MS9414Optimisation Mix, lyophil.2 x 1 x 2 ml
 
ClinChek® Controls:
MS9482Serum Control, lyophil.,2 x 5 x 1 ml
Level I, II
 

Download product brochures, product documents (e.g. safety data sheets), and instructions for use.

Please get in touch to order this product.