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Antimycotics

Invasive fungal infections, predominantly aspergillosis and candidiasis, are the most important causes of morbidity and mortality in immuno-compromised patients. Antimycotics are used for the treatment and prophylaxis of fungal infections. Antifungal drugs show large intra- and interindividual variabilities in pharmacokinetics. The accurate measurement of the individual drug concentration in serum/plasma is essential for therapeutic control and successful results.

The  Add-on Set for Antimycotics (order no. MS9600) contains all analyte specific components required for the determination of 8 drugs and metabolites. 

Sample Preparation


Sample Preparation Antimycotics Serum Plasma

Chromatography



Ordering Information


Order No.


Description


Quantity


MS9000


ClinMass® TDM Platform for 400 assays


1 pce.


Kit Components (order no. MS9000): 


MS9005


Autosampler Washing Solution


1000 ml


MS9007


Mobile Phase A


2 x MS9007 (2x 1000 ml)


MS9008


Mobile Phase B


1000 ml


MS9020


Sample Preparation Vials


4 x MS9020 (4 x 100 pcs.)


MS9021


Precipitant P


2 x MS9021 (2 x 25 ml)


Start Accessories: 


MS9030


Analytical Column with test chromatogram


1 pce.


MS9032


Prefilter


1 pce.


Accessories: 


MS9022


Diluting Solution D


50 ml


MS9600


ClinMass® Add-on Set for Antimycotics in Serum / Plasma for 200 assays


1 pce.


Kit Components (order no. MS9600):


MS9612


Internal Standard IS, lyophil.


5 x 5 ml


MS9613


Serum Calibrator Set, lyophil. (Level 0 – 3)


4 x 1 x 1 ml


 


Manual


 


Start Accessories: 


MS9614


Optimisation Mix, lyophil.


2 ml


ClinChek® Controls: 


MS9682


Serum Control, lyophil., Level I, II


2 x 5 x 1 ml



The ClinMass Add-On Set for Antimycotics (order no. MS9650) contains all analyte specific components required for the determination of 8 drugs and metabolites. The ClinMass® TDMi-Platform (order no. MS9050) contains all components needed for on-line SPE LC-MS/MS analysis. It can be used with all ClinMass® Add-On sets of the TDMi Kit system. The analytical column is suitable for the whole TDM analyte panel.

Sample Preparation

No manual sample preparation needed!
Direct injection of sample and Internal Standard IS
in the ratio 1:2 (autosampler).
Direct injection

Chromatography



Ordering Information


Order No.


Description


Quantity


MS9050


ClinMass® TDM Platform, on-line for 400 assays


1 pce.


Kit Components (order no. 9050):


MS9005


Autosampler Washing Solution


1 x 1000 ml


MS9007


Mobile Phase A


2 x 1000 ml


MS9008


Mobile Phase B


1 x 1000 ml


MS9059


SPE-Buffer Load L


2 x 2500 ml


MS9060


SPE-Buffer Wash W


2 x 2500 ml


MS9071


Reconstitution Solution R


1 x 5ml


Start Accessories:


MS9035


Analytical Column with test chromatogram


1 pce.


MS9031


SPE-Column


1 pce.


MS9032


Prefilter


1 pce.


Accessories:


MS9022


Diluting Solution D


50 ml


FK7400


Inline-Filter (stainless steel sieve, free of dead volume)


1 pce.


FK7340


Sealings and sieves for order no. FK7400


4 pcs. each


MS9650


ClinMass® Add-on Set, on-line, for Antimycotics in Serum / Plasma for 400 assays


1 pce.


Kit Components (order no. MS9650):


MS9662


Internal Standard IS, lyophil.


5 ml


MS9613


Serum Calibrator Set, lyophil. (Level 0 – 3)


4x1x1 ml


Manual


1 pce


Separately available components:


MS9662


Internal Standard IS, lyophil.


5 ml


MS9613


Serum Calibrator Set, lyophil. (Level 0 – 3)


4 x 1 x 1 ml


Start Accessories:


MS9614


Optimisation Mix, lyophil.


2 ml


ClinChek® Controls:


MS9682


Serum Control, lyophil., Level I, II


2 x 5 x 1 ml



Download product brochures, product documents (e.g. safety data sheets), and instructions for use.

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