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CDT

CDT (Carbohydrate Deficient Transferrin) is the most specific parameter for chronic alcohol abuse.

The ClinRep® HPLC Complete Kit for CDT provides a unique chromatographical resolution compared to other commercially available test kits. The analytical method correlates with the reference method of the IFCC-CDT-WG* and ensures a reliable separation of all relevant transferrin isoforms (a-, mono-, di-, …, hexasialotransferrin). This applies in particular for disialotransferrin, which is the defined analyte by this group. Alternatively to this method with manual sample preparation, ClinRep® Complete Kits for on-line analysis and automated on-line analysis via 96-well plates are available.

* Working group of the IFCC for the international standardisation of CDT measurement.

Sample Preparation


sample-preparation-cdt-serum-manual

Chromatography


cdt-serum-chromograph

Ordering Information


Order No.DescriptionQuantity
21000ClinRep® Complete Kit for CDT1 pce.
(Carbohydrate-deficient Transferrin)
in Serum
for 100 assays
Contents:
Mobile Phase A3 x 21007
Mobile Phase B1 x 21008
Mobile Phase C1 x 21009
Sample Preparation Vials2 x 21020
Stabilising Reagent S1 x 21021
Precipitant P11 x 21022
Precipitant P21 x 21023
Diluting Solution D1 x 21024
Manual
Quick Reference
Separately available components:
21007Mobile Phase A2000 ml
21008Mobile Phase B2000 ml
21009Mobile Phase C2000 ml
21013Serum Calibrator Set, lyophil. (Level 1 – 2)2 x 1 x 1 ml
21014Test Solution15 ml
21020Sample Preparation Vials100 pcs.
21021Stabilising Reagent S3 ml
21022Precipitant P11 ml
21023Precipitant P22 ml
21024Diluting Solution D100 ml
Start Accessories:
21030Analytical Column with test chromatogram1 pce.
21032Cartridge incl. 1 Precolumn1 pce.
Refill Service:
21031Analytical Column with test chromatogram1 pce.
(original column needs to be returned)
Accessories:
21033Precolumns5 pcs.
FK5810PEEK tubing (connection of prefilter and column)1 pce.
FW3000Fixed-Wavelength-VIS-Detector (460 nm), complete1 pce.
RC2002Sodium-Hypochlorite-Solution (5 %)12 ml
ClinChek® Controls:
21080Serum Control, lyophil.10 x 1 ml
Level I
21081Serum Control, lyophil.10 x 1 ml
Level II
21082Serum Control, lyophil.2 x 5 x 1 ml
Level I, II

This ClinRep® Complete Kit is designed for the fast analysis of CDT with on-line SPE HPLC. It features an injection interval of 9.5 min only and provides a unique chromatographical resolution compared to other commercially available test kits. Analogously to our kit with manual sample preparation, the on-line procedure correlates with the candidate reference method of the IFCC-CDT-WG*. Prior to the sample injection, a simple dilution step is required (”sample pre-treatment“, see below). Alternatively, the dilution can be performed automated via 96-well plates. For this purpose an additional ClinRep® Complete Kit is available.

Sample Pretreatment

sample-pretreatment-cdt-serum-on-line

Chromatography

cdt-serum-on-line-chromograph

Ordering Information

Order No.DescriptionQuantity
21100ClinRep® Complete Kit for CDT1 pce.
(Carbohydrate-deficient Transferrin)
in Serum
for 300 assays
Contents:
Mobile Phase A3 x 21007
Mobile Phase B1 x 21008
Mobile Phase C2 x 21009
Vials for Sample Pretreatment with Diluting Solution6 x 21120
Manual
Quick Reference
Separately available components:
21007Mobile Phase A2000 ml
21008Mobile Phase B2000 ml
21009Mobile Phase C2000 ml
21013Serum Calibrator Set, lyophil. (Level 1 – 2)2 x 1 x 1 ml
21014Test Solution15 ml
21120Vials for Sample Pretreatment with Diluting Solution50 pcs.
Start Accessories:
21030Analytical Column with test chromatogram1 pce.
21032Cartridge incl. 1 Precolumn1 pce.
FK5820Stainless steel prefilter holder incl. 1 prefilter1 pce.
FK7400Inline-Filter (stainless steel sieve, free of dead volume)1 pce.
Refill Service:
21031Analytical Column with test chromatogram1 pce.
(original column needs to be returned)
Accessories:
21033Precolumns5 pcs.
FK1102Switching valve Sykam (6-port / 3-channel incl. electr. drive, PEEK)1 pce.
FK5810PEEK tubing (connection of prefilter and column)1 pce.
FK5821Replacement filter for Stainless steel prefilter holder10 pcs.
FK7340Sealings and sieves for order no. FK74004 pcs. each
FW3000Fixed-Wavelength-VIS-Detector (460 nm), complete1 pce.
RC2002Sodium-Hypochlorite-Solution (5 %)12 ml
ClinChek® Controls:
21080Serum Control, lyophil.10 x 1 ml
Level I
21081Serum Control, lyophil.10 x 1 ml
Level II
21082Serum Control, lyophil.2 x 5 x 1 ml
Level I, II

This ClinRep® Complete Kit is designed for the fully automated analysis of CDT with liquid handling systems and subsequent on-line SPE HPLC. The analytical method correlates with the candidate reference method of the IFCC-CDT-WG* and ensures a reliable separation of all relevant transferrin isoforms (a-, mono-, di-, …, hexa-sialotransferrin). This applies in particular for disialotransferrin, which is the defined analyte by this group. An accurate calculation of the CDT value is ensured by baseline separation.

* Working group of the IFCC for the international standardisation of CDT measurement.

Sample Pretreatment (Liquid Handling System)


sample-pretreatment-cdt-in-serum-automated-on-line

Chromatography


cdt-serum-on-line-chromograph

Ordering Information


Order No.DescriptionQuantity
21200ClinRep® Complete Kit for CDT1 pce.
(Carbohydrate-deficient Transferrin)
in Serum
for 300 assays
Contents:
Mobile Phase A3 x 21007
Mobile Phase B1 x 21008
Mobile Phase C2 x 21009
Diluting Solution D3 x 21221
Manual
Quick Reference
Separately available components:
21007Mobile Phase A2000 ml
21008Mobile Phase B2000 ml
21009Mobile Phase C2000 ml
21013Serum Calibrator Set, lyophil. (Level 1 – 2)2 x 1 x 1 ml
21014Test Solution15 ml
21221Diluting Solution D50 ml
Start Accessories:
21030Analytical Column with test chromatogram1 pce.
21032Cartridge incl. 1 Precolumn1 pce.
FK5820Stainless steel prefilter holder incl. 1 prefilter1 pce.
FK7400Inline-Filter (stainless steel sieve, free of dead volume)1 pce.
Refill Service:
21031Analytical Column with test chromatogram1 pce.
(original column needs to be returned)
Accessories:
21033Precolumns5 pcs.
FK1102Switching valve Sykam (6-port / 3-channel incl. electr. drive, PEEK)1 pce.
FK5810PEEK tubing (connection of prefilter and column)1 pce.
FK5821Replacement filter for Stainless steel prefilter holder10 pcs.
FK651296-Well-Plates (500 µl)8 pcs.
FK7340Sealings and sieves for order no. FK74004 pcs. each
FW3000Fixed-Wavelength-VIS-Detector (460 nm), complete1 pce.
RC2002Sodium-Hypochlorite-Solution (5 %)12 ml
ClinChek® Controls:
21080Serum Control, lyophil.10 x 1 ml
Level I
21081Serum Control, lyophil.10 x 1 ml
Level II
21082Serum Control, lyophil.2 x 5 x 1 ml
Level I, II

Download product brochures, product documents (e.g. safety data sheets), and instructions for use.

Please get in touch to order this product.