Products / LC-MS/MS ClinMass® Complete Kits
Free Metanephrines
Plasma free metanephrines (PFM) are the most specific parameters for the diagnosis of extraadrenal chromaffin tumors. The measurement of PFMs (metanephrine (M), normetanephrine (NM) and 3-methoxytyramine (MT)) is challenging because of their polar nature, their low molecular weight and their low physiological concentration in human plasma.
This ClinMass® Complete Kit represents a reliable and standardised method for the determination of PFM. In contrast to most of the LC-MS/MS methods established in clinical routine analysis, this method does not require dilution or evaporation steps. The measurement of highly concentrated samples is guaranteed. Alternatively to this method with manual sample preparation for standard LC-MS/MS systems, RECIPE offers an LC-MS/MS Complete Kit with on-line SPE analysis.
Sample Preparation
Chromatography
Ordering Information
| Order No. | Description | Quantity |
|---|---|---|
| MS11100 | ClinMass® Complete Kit for Free Metanephrines in Plasma | 1 pce. |
| for 200 assays | ||
| Content | ||
| Autosampler Washing Solution | 1 x MS11005 | |
| Mobile Phase A | ||
| Mobile Phase B | ||
| Internal Standard IS | ||
| Serum Calibrator Set, lyophil. (Level 0 – 4) | ||
| Sample Preparation Columns | ||
| Washing Solution W1 | 1 x MS11121 | |
| Washing Solution W2 | 1 x MS11122 | |
| Washing Solution W3 | 1 x MS11123 | |
| Eluting Reagent E | 1 x MS11124 | |
| Manual | ||
| Separately available components: | ||
| MS11005 | Autosampler Washing Solution | 1000 ml |
| MS11007 | Mobile Phase A | 250 ml |
| MS11008 | Mobile Phase B | 1000 ml |
| MS11112 | Internal Standard IS | 50 ml |
| MS11013 | Serum Calibrator Set, lyophil. (Level 0 – 4) | 5 x 1 x 3 ml |
| MS11014 | Optimisation Mix | 2 ml |
| MS11120 | Sample Preparation Columns | 50 pcs. |
| MS11121 | Washing Solution W1 | 400 ml |
| MS11122 | Washing Solution W2 | 400 ml |
| MS11123 | Washing Solution W3 | 200 ml |
| MS11124 | Eluting Reagent E | 40 ml |
| Start Accessories: | ||
| MS11030 | Analytical Column with test chromatogram | 1 pce. |
| Accessories: | ||
| MS11161 | Elution Vials | 100 pcs. |
| ClinChek® Controls: | ||
| MS11080 | Serum Control, lyophil., Level I | 10 x 3 ml |
| MS11081 | Serum Control, lyophil., Level II | 10 x 3 ml |
| MS11082 | Serum Control, lyophil., Level III | 10 x 3 ml |
| MS11083 | Serum Control, lyophil., Level I, II, III | 3 x 3 x 3 ml |
Most LC-MS/MS methods used in clinical routine analysis involve time- and labour-consuming manual sample preparation for solid phase extraction (SPE). In contrast to this the RECIPE ClinMass® Complete Kit provides a simple sample pretreatment with one-step protein precipitation and subsequent on-line SPE.
Sample Pretreatment
Chromatography
Ordering Information
| Order No. | Description | Quantity |
|---|---|---|
| MS11000 | ClinMass® Complete Kit for Free Metanephrines in Plasma – on-line Analysis for 200 assays | 1 pce. |
| Kit Components (order no. MS11000): |
||
| MS11005 | Autosampler Washing Solution | 1000 ml |
| MS11007 | Mobile Phase A | 250 ml |
| MS11008 | Mobile Phase B | 2 x MS11008 (2 x 1000 ml) |
| MS11009 | SPE-Buffer Load L | 2 x MS11009 (2 x 1000 ml) |
| MS11010 | SPE-Buffer Wash W | 1000 ml |
| MS11012 | Precipitant P with Internal Standard | 30 ml |
| MS11013 | Serum Calibrator Set, lyophil. (Level 0 – 4) | 5 x 1 x 3 ml |
| MS11014 | Optimisation Mix | 2 ml |
| MS11020 | Sample Pretreatment Vials | 2 x MS11020 (2 x 100 pcs.) |
| Manual | 1 pce. |
|
| Start Accessories: |
||
| MS11030 | Analytical Column with test chromatogram | 1 pce. |
| MS11031 | SPE-Column | 1 pce. |
| ClinChek® Controls: |
||
| MS11080 | Serum Control, lyophil., Level I | 10 x 3 ml |
| MS11081 | Serum Control, lyophil., Level II | 10 x 3 ml |
| MS11082 | Serum Control, lyophil., Level III | 10 x 3 ml |
| MS11083 | Serum Control, lyophil., Level I, II, III | 3 x 3 x 3 ml |
Download product brochures, product documents (e.g. safety data sheets), and instructions for use.
