Free Metanephrines

Plasma free metanephrines (PFM) are the most specific parameters for the diagnosis of extraadrenal chromaffin tumors. The measurement of PFMs (metanephrine (M), normetanephrine (NM) and 3-methoxytyramine (MT)) is challenging because of their polar nature, their low molecular weight and their low physiological concentration in human plasma.

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