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Steroids

Steroid hormones are synthesised from cholesterol. The majority of these powerful molecules are produced by the adrenal glands, testes or ovaries. They fulfil a wide range of physiological functions after binding to specific cell receptors of various target organs. Mainly they are involved in the carbohydrate, lipid and protein metabolism, stress response and in the regulation of the water and mineral balances, in reproductive processes and the development of secondary sex characteristics. Consequently steroid hormones are also involved in a variety of diseases, like adrenal tumors, the Adrenogenital syndrome (CAH), the Cushing’s syndrome or the Polycystic Ovarian Syndrome. The quantitative profiling of steroids is essential in diagnosis and evaluation of pathologic conditions and therapeutic responses.

RECIPE developed a fast and simple quantitative Steroid profiling LC-MS/MS method that covers the most relevant steroid hormones.

Sample Preparation


Sample Pretreatment Steroids Plasma Serum

Chromatography


Chromatogram Steroids Plasma Serum

Ordering Information


Order No.


Description


Quantity


MS12000


ClinMass® Complete Kit for Steroids in Serum / Plasma for 200 assays


1 pce.


Kit Components (order no. MS12000):


MS12005


Autosampler Washing Solution


1000 ml


MS12008


Mobile Phase A


1000 ml


MS12009


Mobile Phase B


800 ml


MS12012


Internal Standard IS


10 ml


MS12013


Serum Calibrator Set, lyophil. (Level 0 – 6)


7 x 1 x 2 ml


MS12020


Sample Preparation Vials


100 pcs.


MS12021


Precipitant P


5 ml


Manual


Additional components:


MS12014


Optimix


2 x 1 x 2 ml


Start Accessories:


MS12030


Analytical Column with test chromatogram


1 pce.


ClinChek® Controls:


MS12083


Serum Control, lyophil., Level I, II, III


3 x 3 x 2 ml



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