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Tricyclic Antidepressants

Tricyclic antidepressants (TCA) are a group of psychoactive drugs which are mainly used for the therapy of endogene depressions, anxiety and in the pain management.

The ClinMass® Add-on Set for TCAs (order no.MS9100) contains all analyte specific components required for the quantification of 13 TCAs + 2 neuroleptics. The ClinMass® TDM Platform (order no. MS9000) contains the components needed for sample preparation and LC-MS/MS analysis. It can be used with all ClinMass® Add-on Sets of the TDM Kit System (BZP, TCA, …).

Sample Preparation



Chromatography


Chromatogram Tricyclic Antidepressants Serum Plasma

Ordering Information


Order No.


Description


Quantity


MS9000


ClinMass® TDM Platform for 400 assays


1 pce.


Kit Components (order no. MS9000):


MS9005


Autosampler Washing Solution


1000 ml


MS9007


Mobile Phase A


2 x MS9007 (2 x 1000 ml)


MS9008


Mobile Phase B


1000 ml


MS9020


Sample Preparation Vials


4 x MS9020 (4 x 100 pcs.)


MS9021


Precipitant P


2 x MS9021 (2 x 25 ml)


Start Accessories:


MS9030


Analytical Column with test chromatogram


1 pce.


MS9032


Prefilter


1 pce.


Accessories:


MS9022


Diluting Solution D


50 ml


MS9100


ClinMass® Add-on Set for Tricyclic Antidepressants in Serum / Plasma for 200 assays


1 pce.


Kit Components (order no. MS9100):


MS9112


Internal Standard IS, lyophil.


5 x 5 ml


MS9113


Serum Calibrator Set, lyophil. (Level 0 – 3)


4 x 1 x 1 ml


Manual


1 pce.


Start Accessories:


MS9114


Optimisation Mix, lyophil.


2 x 2 ml


ClinChek® Controls:


MS9182


Serum Control, lyophil., Level I, II


2 x 5 x 1 ml



The ClinMass® Add-on Set for TCAs (order no. MS9150) contains all analyte specific components required for the quantification of 13 TCAs and 2 atypical neuroleptics. The ClinMass® TDM Platform (order no. MS9050) contains the components needed for on-line SPE LCMS/ MS analysis. It can be used with all ClinMass® Add-on Sets of the “TDM Kit System, on-line” (BZP, TCA, …). The analytical column is suitable for the whole analyte panel (153 compounds).

Sample Preparation


Direct injection

Chromatography



Ordering Information


Order No.


Description


Quantity


MS9050


ClinMass® TDM Platform, on-line for 400 assays


1 pce.


Kit Components (order no. MS9050):


MS9005


Autosampler Washing Solution


1000 ml


MS9007


Mobile Phase A


2 x MS9007 (2 x 1000 ml)


MS9008


Mobile Phase B


1000 ml


MS9059


SPE-Buffer Load L


2 x MS9059 (2 x 2500 ml)


MS9060


SPE-Buffer Wash W


2 x MS9060 (2 x 2500 ml)


MS9071


Reconstitution Solution R


5 ml


Start Accessories:


MS9035


Analytical Column with test chromatogram


1 pce.


MS9031


SPE-Column


1 pce.


MS9032


Prefilter


1 pce.


Accessories:


MS9022


Diluting Solution D


50 ml


FK7400


Inline-Filter (stainless steel sieve, free of dead volume)


1 pce.


FK7340


Sealings and sieves


4 pcs. each


MS9150


ClinMass® Add-on Set, on-line, for Tricyclic Antidepressants in Serum / Plasma for 400 assays


1 pce.


Kit Components (order no. MS9150):


MS9162


Internal Standard IS, lyophil.


5 ml


MS9113


Serum Calibrator Set, lyophil. (Level 0 – 3)


4 x 1 x 1 ml


Manual


1 pce.


Start Accessories:


MS9114


Optimisation Mix, lyophil.


2 x 2 ml


ClinChek® Controls:


MS9182


Serum Control, lyophil., Level I, II


2 x 5 x 1 ml



Download product brochures, product documents (e.g. safety data sheets), and instructions for use.

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