Products / LC-MS/MS ClinMass® Complete Kits
Methylmalonic Acid, advanced
Methylmalonic acid (MMA) serves for the assessment of the vitamin B12 status. Vitamin B12 deficiency leads to an increased MMA concentration in serum, plasma and urine.
The RECIPE ClinMass® Complete Kit provides a fast MMA analysis featuring short sample preparation with only one pipetting step (serum, plasma) or direct injection of samples after dilution and addition of IS (urine). The subsequent LC-MS/MS analysis is performed within a 2 min injection interval only while the isobar component succinic acid, which may interfere with MMA, is reliably separated. The method is fully validated using only one (serum) calibration and control set for all three sample matrices (ClinCal® 4-Level Calibrator Set and ClinChek® Controls).
Sample Preparation
Chromatography
Ordering Information
| Order No. | Description | Quantity |
|---|---|---|
| MS5100 | ClinMass® Complete Kit, advanced, for Methylmalonic Acid in Serum / Plasma / Urine for 300 assays | 1 pce. |
| Kit Components (order no. MS5100): |
||
| MS5005 | Autosampler Washing Solution | 1000 ml |
| MS5108 | Mobile Phase A | 1000 ml |
| MS5109 | Mobile Phase B | 200 ml |
| MS5112 | Precipitant P with Internal Standard | 3 x MS5112 (3 x 40 ml) |
| MS5013 | Serum Calibrator Set, lyophil., (Level 0 – 3) | 4 x 1 x 2 ml |
| MS5020 | Sample Preparation Vials | 3 x MS5020 (3 x 100 pcs.) |
| Manual | 1 pce. |
|
| Additional Components: |
||
| MS5114 | Optimisation Mix | 2 ml |
| MS5021 | Diluting Solution D for Urine | 50 ml |
| Start Accessories: |
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| MS5130 | Analytical Column with test chromatogram | 1 pce. |
| ClinChek® Controls: |
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| MS5080 | Serum Control, lyophil., Level I | 10 x 2 ml |
| MS5081 | Serum Control, lyophil., Level II | 10 x 2 ml |
| MS5082 | Serum Control, lyophil., Level I, II | 2 x 5 x 2 ml |
Download product brochures, product documents (e.g. safety data sheets), and instructions for use.
