Products / LC-MS/MS ClinMass® Complete Kits
Methylmalonic Acid, advanced
Methylmalonic acid (MMA) serves for the assessment of the vitamin B12 status. Vitamin B12 deficiency leads to an increased MMA concentration in serum, plasma and urine.
manual sample preparation
The RECIPE ClinMass® Complete Kit provides a fast MMA analysis featuring short sample preparation with only one pipetting step (serum, plasma) or direct injection of samples after dilution and addition of IS (urine). The subsequent LC-MS/MS analysis is performed within a 2 min injection interval only while the isobar component succinic acid, which may interfere with MMA, is reliably separated. The method is fully validated using only one (serum) calibration and control set for all three sample matrices (ClinCal® 4-Level Calibrator Set and ClinChek® Controls).
Sample Preparation
Chromatography
Ordering Information
| Order No. | Description | Quantity |
|---|---|---|
| MS5100 | ClinMass® Complete Kit, advanced, | 1 pce. |
| for Methylmalonic Acid in Serum / Plasma / Urine | ||
| for 300 assays | ||
| Contents: | ||
| Autosampler Washing Solution | 1 x MS5005 | |
| Mobile Phase A | 1 x MS5208 | |
| Mobile Phase B | 1 x MS5209 | |
| Precipitant P with Internal Standard | 3 x MS5112 | |
| Serum Calibrator Set, lyophil. (Level 0 – 3) | 1 x MS5013 | |
| Sample Preparation Vials | 3 x MS5020 | |
| Manual | ||
| Separately available components: | ||
| MS5005 | Autosampler Washing Solution | 1000 ml |
| MS5208 | Mobile Phase A | 1000 ml |
| MS5209 | Mobile Phase B | 330 ml |
| MS5112 | Precipitant P with Internal Standard | 40 ml |
| MS5013 | Serum Calibrator Set, lyophil. (Level 0 – 3) | 4 x 1 x 2 ml |
| MS5114 | Optimisation Mix | 2 ml |
| MS5020 | Sample Preparation Vials | 100 pcs. |
| MS5021 | Diluting Solution D for Urine | 50 ml |
| Start Accessory: | ||
| MS5130 | Analytical Column with test chromatogram | 1 pce. |
| ClinChek® Controls: | ||
| MS5082 | Serum Control, lyophil., | 2 x 5 x 2 ml |
| Level I, II |
Download product brochures, product documents (e.g. safety data sheets), and instructions for use.
